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Proteintech
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Immunogen sequence: VQPQKRKPK TGILMLNMGG PETLGDVHDF LLRLFLDRDL MTLPIQNKLA PFIAKRRTPK IQEQYRRIGG GSPIKIWTSK QGEGMVKLLD ELSPNTAPHK YYIGFRYVHP LTEEAIEEME RDGLERAIAF TQYPQYSCST TGSSLNAIYR YYNQVGRKPT MKWSTIDRWP THHLLIQCFA DHILKELDHF PLEKRSEVVI LFSAHSLPMS VVNRGDPYPQ EVSATVQKVM ERLEYCNPYR LVWQSKVGPM PWLGPQTDES IKGLCERGRK NILLVPIAFT SDHIETLYEL DIEYSQVLAK ECGVENIRRA ESLNGNPLFS KALADLVHSH IQSNELCSKQ LTLSCPLCVN PVCRETKSFF TSQQL (60-423 aa encoded by B C039841)
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ferrochelatase, mitochondrial; Heme synthase; heme synthetase; Protoheme ferro-lyase; protoporphyria
基因别名: AI894116; EPP; FCE; fch; Fcl; FECH
UniProt ID: (Human) P22830, (Mouse) P22315
Entrez Gene ID: (Human) 2235, (Rat) 361338, (Mouse) 14151