Search
Proteintech
FEV Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
25058-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FEV Fusion Protein Ag20647 (1-238 aa encoded by BC023511)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.45 mg/mL
规格
67.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MRQSGASQP LLINMYLPDP VGDGLFKDGK NPSWGPLSPA VQKGSGQIQL WQFLLELLAD RANAGCIAWE GGHGEFKLTD PDEVARRWGE RKSKPNMNYD KLSRALRYYY DKNIMSKVHG KRYAYRFDFQ GLAQACQPPP AHAHAAAAAA AAAAAAQDGA LYKLPAGLAP LPFPGLSKLN LMAASAGVAP AGFSYWPGPG PAATAAAATA ALYPSPSLQP PPGPFGAVAA ASHLGGHYH (1-238 aa encoded by BC023511 )
靶标信息
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ETS-domain transcription factor Pet-1; FEV (ETS oncogene family); FEV (fifth Ewing variant); FEV, ETS transcription factor; fifth Ewing variant protein; mPet-1; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; pheochromocytoma 12 ETS (E26 transformation-specific); plasmacytoma expressed transcript 1
基因别名: HSRNAFEV; mPet-1; PET-1; Pet1; Pex1
UniProt ID: (Human) Q99581, (Mouse) Q8QZW2
Entrez Gene ID: (Human) 54738, (Mouse) 260298
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of gene expression
neuron maturation
maternal behavior
neuron fate specification
regulation of serotonin uptake
regulation of serotonin biosynthetic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
