Invitrogen

FGF20 Polyclonal Antibody

查看其他5个FGF20抗体

产品信息

PA5-50665

应用	建议稀释比	已发表文章
免疫组化（石蜡） (IHC (P))	1:25-1:100	-

产品规格
种属反应	Human, Mouse, Rat
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	Synthetic peptide corresponding to a region derived from internal residues of human fibroblast growth factor 20
偶联物	Unconjugated
形式	Liquid
浓度	0.6 mg/mL
纯化类型	Antigen affinity chromatography
保存液	PBS, pH 7.4, with 40% glycerol
内含物	0.05% sodium azide
保存条件	-20°C
RRID	AB_2636117

产品详细信息

The antibody detects endogenous levels of total FGF20 protein.

靶标信息

FGF-20 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through FGFR 2c and 3c, and is expressed during limb and brain development.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: FGF; FGF-20; Fibroblast growth factor; Fibroblast growth factor 20

基因别名: FGF-20; FGF20; RHDA2

UniProt ID: (Human) Q9NP95, (Rat) Q9EST9, (Mouse) Q9ESL9

Entrez Gene ID: (Human) 26281, (Rat) 66017, (Mouse) 80857

分子生物学功能: growth factor intercellular signal molecule

MAPK cascade signal transduction cell-cell signaling positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation phosphatidylinositol-3-phosphate biosynthetic process positive regulation of GTPase activity phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling regulation of cardiac muscle cell proliferation inner ear receptor cell differentiation positive regulation of ERK1 and ERK2 cascade cell differentiation

参与通路

protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity fibroblast growth factor receptor binding growth factor activity 1-phosphatidylinositol-3-kinase activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity receptor binding