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Proteintech
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This polyclonal antibody raised against 358-704 aa of human FGFR2 can cross react with other members of the FGFR family.
Immunogen sequence: EFPRDKLTL GKPLGEGCFG QVVMAEAVGI DKDKPKEAVT VAVKMLKDDA TEKDLSDLVS EMEMMKMIGK HKNIINLLGA CTQDGPLYVI VEYASKGNLR EYLRARRPPG MEYSYDINRV PEEQMTFKDL VSCTYQLARG MEYLASQKCI HRDLAARNVL VTENNVMKIA DFGLARDINN IDYYKKTTNG RLPVKWMAPE ALFDRVYTHQ SDVWSFGVLM WEIFTLGGSP YPGIPVEELF KLLKEGHRMD KPANCTNELY MMMRDCWHAV PSQRPTFKQL VEDLDRILTL TTNEEYLDLS QPLEQYSPSY PDTRSSCSSG DDSVFSPDPM PYEPCLPQYP HINGSVKT (358-704 aa encoded by BC039243)
FGFR2 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR family members differ from one another in their ligand affinities and tissue distribution. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bacteria-expressed kinase; BEK fibroblast growth factor receptor; CD332; FGF Receptor; FGF Receptor 2; FGF-10; FGFR; FGFR-2; Fibroblast growth factor receptor 2; K-sam; Keratinocyte growth factor receptor; KGFR; protein tyrosine kinase, receptor like 14; Soluble KGFR
基因别名: BBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; FGFR2; JWS; K-SAM; KGFR; KSAM; TK14; TK25
UniProt ID: (Human) P21802
Entrez Gene ID: (Human) 2263