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Proteintech
FKBP6 Polyclonal Antibody
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产品信息
19163-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FKBP6 Fusion Protein Ag4642 (4-327 aa encoded by BC036817)
偶联物
形式
Liquid
浓度
0.37 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SALNQGVLE GDDAPGQSLY ERLSQRMLDI SGDRGVLKDV IREGAGDLVA PDASVLVKYS GYLEHMDRPF DSNYFRKTPR LMKLGEDITL WGMELGLLSM RRGELARFLF KPNYAYGTLG CPPLIPPNTT VLFEIELLDF LDCAESDKFC ALSAEQQDQF PLQKVLKVAA TEREFGNYLF RQNRFYDAKV RYKRALLLLR RRSAPPEEQH LVEAAKLPVL LNLSFTYLKL DRPTIALCYG EQALIIDQKN AKALFRCGQA CLLLTEYQKA RDFLVRAQKE QPFNHDINNE LKKLASCYRD YVDKEKEMWH RMFAPCGDGS TAGES (4-327 aa encoded by BC036817)
靶标信息
FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 36 kDa FK506-binding protein; 36 kDa FKBP; FK506 binding protein 6, 36kDa; FK506-binding protein 6; FK506-binding protein 6 (36kD); FKBP-6; Immunophilin FKBP36; Inactive peptidyl-prolyl cis-trans isomerase FKBP6; Inactive PPIase FKBP6; MGC87179; peptidyl-prolyl cis-trans isomerase FKBP6; PPIase FKBP6; rotamase
基因别名: 1700008G22Rik; 36kDa; AU017274; D5Ertd724e; FKBP-36; FKBP-6; FKBP36; FKBP6
UniProt ID: (Human) Q7Z4T4, (Mouse) Q91XW8
Entrez Gene ID: (Human) 8468, (Mouse) 94244
protein peptidyl-prolyl isomerization
protein folding
meiotic nuclear division
spermatogenesis
cell differentiation
gene silencing by RNA
piRNA metabolic process
DNA methylation involved in gamete generation
positive regulation of viral genome replication
chaperone-mediated protein folding
peptidyl-proline modification
meiotic cell cycle
