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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
0.5 µg/mL | 查看1篇已发表文章 1篇已发表文章 |
免疫细胞化学 (ICC/IF) |
10 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
已发表种属 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS |
内含物 |
0.02% sodium azide |
保存条件 |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C |
RRID |
AB_11154443 |
In Western blot applications, this antibody detects a band at ~220kDa. A suggested positive control is Hela cell lysate.
PA5-19954 can be used with blocking peptide PEP-0079.
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CASP8 associated protein 2; CASP8-associated protein 2; CASP8AP2; FLASH homolog RIP25; FLICE associated huge; FLICE-associated huge protein; FLJ11208; human FLASH; RP11-63K6.3
基因别名: CASP8AP2; CED-4; FLASH; KIAA1315; RIP25
UniProt ID: (Human) Q9UKL3
Entrez Gene ID: (Human) 9994
分子生物学功能:
protein-binding activity modulator
