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Abnova
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPSGCHSSPP SGLRGDMASL VPLSPYLSPT VLLLVSCDLG FVRADRPPSP VNVTVTHLRA NSATVSWDVP EGNIVIGYSI SQQRQNGPGQ RVIREVNTTT RACALWGLAE DSDYTVQVRS IGLRGESPPG PRVHFRTLKG SDRLPSNSSS PGDITVEGLD GERPLQTGEV VIIVVVLLMW AAVIGLFCRQ YDIIKDNDSN NNPKEKGKGP EQSPQGRPVG TRQKKSPSIN TIDV
Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Fibronectin type III domain-containing protein 4; Fibronectin type III repeat-containing protein 1
基因别名: FNDC4; FRCP1; UNQ6389/PRO21134
Entrez Gene ID: (Human) 64838