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Invitrogen
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Immunogen sequence: DRPPSPVNVT VTHLRANSAT VSWDVPEGNI VIGYSISQQR QNGPGQRVIR EVNTTTRACA LWGLAEDSDY TVQVRSIGLR GESPPGPRVH FRTLKGSDRL PSNSSSPGDI TVEGLDGERP LQT
Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Fibronectin type III domain-containing protein 4; fibronectin type III repeat containing protein 1; Fibronectin type III repeat-containing protein 1
基因别名: 2810430J06Rik; 6330410H20Rik; AB030187; AI838506; AW487863; FNDC4; Fnmp1; FRCP1; UNQ6389/PRO21134
UniProt ID: (Human) Q9H6D8, (Mouse) Q3TR08
Entrez Gene ID: (Human) 64838, (Mouse) 64339