Proteintech

FNTB Monoclonal Antibody (1F3B10)

Name: FNTB Monoclonal Antibody (1F3B10)
Brand: Proteintech
SKU: 66783-1-IG

查看其他13个FNTB抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (5)

FNTB Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 5

FNTB Antibody (66783-1-IG) in ICC/IF

Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using FNTB antibody (Product # 66783-1-IG, Clone: 1F3B10 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

Product Image Gallery

Immunogen image

Immunogen Image FNTB Monoclonal Antibody (1F3B10)

产品信息

66783-1-IG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:4,000

免疫细胞化学 (ICC/IF)

1:800

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

1F3B10

抗原

FNTB Fusion Protein Ag27796 (1-356 aa encoded by BC020232)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MASPSSFTY YCPPSSSPVW SEPLYSLRPE HARERLQDDS VETVTSIEQA KVEEKIQEVF SSYKFNHLVP RLVLQREKHF HYLKRGLRQL TDAYECLDAS RPWLCYWILH SLELLDEPIP QIVATDVCQF LELCQSPEGG FGGGPGQYPH LAPTYAAVNA LCIIGTEEAY DIINREKLLQ YLYSLKQPDG SFLMHVGGEV DVRSAYCAAS VASLTNIITP DLFEGTAEWI ARCQNWEGGI GGVPGMEAHG GYTFCGLAAL VILKRERSLN LKSLLQWVTS RQMRFEGGFQ GRCNKLVDGC YSFWQAGLLP LLHRALHAQG DPALSMSHWM FHQQALQEYI LMCCQCPAGG LLDKPGK (1-356 aa encoded by BC020232)

靶标信息

Eukaryotic cells contain 3 different types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in a variety of proteins. These posttranslational modifications provide a mechanism for membrane localization of proteins that lack a transmembrane domain. CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This enzyme has the ability to farnesylate peptides as short as 4 residues in length that conform to the CAAX consensus sequence. The gene for the beta subunit of CAAX farnesyltransferase (FNTB) has been pinpointed to 14q23-q24 by Southern blot hybridization and PCR analyses of panels of human/Chinese hamster somatic cell hybrid lines and by fluorescence chromosomal in situ hybridization.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: CAAX farnesyltransferase subunit beta; EC 2.5.1.58; ft beta; FTase beta; FTase-beta; Protein farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit beta

查看更多收起

基因别名: 2010013E13Rik; AA409500; FNTB; FPTB

查看更多收起

UniProt ID: (Human) P49356, (Mouse) Q8K2I1

查看更多收起

Entrez Gene ID: (Human) 2342, (Mouse) 110606

查看更多收起

功能