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Invitrogen
FOXE1 Polyclonal Antibody
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产品信息
PA5-27143
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FOXE1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLaS3.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
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生物信息学
蛋白别名: forkhead box E2; Forkhead box protein E1; Forkhead box protein E2; forkhead, drosophila, homolog-like 15; Forkhead-related protein FKHL15; HFKH4; HFKL5; HNF-3/fork head-like protein 5; Thyroid transcription factor 2; TTF-2
基因别名: FKHL15; FOXE1; FOXE2; HFKH4; HFKL5; NMTC4; TITF2; TTF-2; TTF2
UniProt ID: (Human) O00358
Entrez Gene ID: (Human) 2304
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
thyroid hormone generation
anatomical structure morphogenesis
cell migration
thyroid gland development
hair follicle morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
thymus development
embryonic organ morphogenesis
hard palate development
soft palate development
pharynx development
