Invitrogen

FOXN1 Polyclonal Antibody

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FOXN1 Antibody (720152) in WB

Western blot analysis was performed on nuclear enriched cell extracts (30 µg lysate) of Raji (Lane 1), A549 (Lane 2) and PC-12 (Lane 3). The blots were probed with Anti- FOXN1 Rabbit Polyclonal Antibody (Product # 720152, 0.5-1 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A 69 kDa band corresponding to FOXN1 was observed across cell lines tested. Known quantity of protein samples were electrophoresed using Nove... View More

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产品信息

720152

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.5-1 µg/mL

免疫细胞化学 (ICC/IF)

1 µg/mL

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide pair corresponding to Human FOXN1 (aa 377-395; 633-646)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2, with 0.1% BSA, 30% glycerol

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2610353

产品详细信息

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.

靶标信息

FOXN1 is a 648 amino acid protein belonging to the winged helix/forkhead family It contains 1 fork-head DNA-binding domain and is a transcriptional regulator involved in development. FOXN1 is involved in directing lineage choices of multi-potential progenitor epithelial cells and controls important regulating genes of lympho-epithelial interactions. It modulates keratinocyte differentiation in hair follicles and nail apparatus and its defects lead to T-cell immunodeficiency congenital alopecia, nail dystrophy, macroscopic nudity and an inborn dysgenesis of the thymus.

仅用于科研。不用于诊断过程。未经明确授权不得转售。