FIGURE: 1 / 2
Immunogen sequence: MGPVMPPSKK PESSGISVSS GLSQCYGGSG FSKALQEDDD LDFSLPDIRL EEGAMEDEEL T
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
FOXN3 is a member of the forkhead/winged helixtranscription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Check point suppressor 1 suppresses multiple yeast checkpoint mutationsincluding mec1, rad9, rad53 and dun1 by activating aMEC1-independent checkpoint pathway. Alternative splicing isobserved at the locus, resulting in distinct isoforms.
Protein Aliases: Checkpoint suppressor 1; CHES; Forkhead box protein N3
Gene Aliases: C14orf116; CHES1; FOXN3; PRO1635
UniProt ID: (Human) O00409
Entrez Gene ID: (Human) 1112