Product References
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.
Cell
Reticker-Flynn NE,Zhang W,Belk JA,Basto PA,Escalante NK,Pilarowski GOW,Bejnood A,Martins MM,Kenkel JA,Linde IL,Bagchi S,Yuan R,Chang S,Spitzer MH,Carmi Y,Cheng J,Tolentino LL,Choi O,Wu N,Kong CS,Gentles AJ,Sunwoo JB,Satpathy AT,Plevritis SK,Engleman EG
14-4771-80 was used in Flow Cytometry to show that an epigenetically instilled tumor-intrinsic interferon response program confers enhanced LN metastatic potential by enabling the evasion of NK cells and promoting LN colonization.
Thu May 26 00:00:00 EDT 2022
Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen.
Cell reports
Boccasavia VL,Bovolenta ER,Villanueva A,Borroto A,Oeste CL,van Santen HM,Prieto C,Alonso-López D,Diaz-Muñoz MD,Batista FD,Alarcón B
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Tue Mar 16 00:00:00 EDT 2021
Multi-color Flow Cytometry for Comprehensive Analysis of the Tumor Immune Infiltrate in a Murine Model of Breast Cancer.
Bio-protocol
Almeida AS,Fein MR,Egeblad M
14-4771-80 was used in Flow cytometry/Cell sorting to describe a detailed procedure for preparing a single-cell suspension from mammary tumors of the mouse mammary tumor virus-polyoma middle T (MMTV-PyMT) and analyzing these cells by multi-color flow cytometry.
Sat Jun 05 00:00:00 EDT 2021
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer.
Nature
Yao W,Rose JL,Wang W,Seth S,Jiang H,Taguchi A,Liu J,Yan L,Kapoor A,Hou P,Chen Z,Wang Q,Nezi L,Xu Z,Yao J,Hu B,Pettazzoni PF,Ho IL,Feng N,Ramamoorthy V,Jiang S,Deng P,Ma GJ,Den P,Tan Z,Zhang SX,Wang H,Wang YA,Deem AK,Fleming JB,Carugo A,Heffernan TP,Maitra A,Viale A,Ying H,Hanash S,DePinho RA,Draetta GF
14-4771 was used in Immunohistochemistry-immunofluorescence to investigate if a mechanistic link between KRAS* signaling and a targetable molecule driving nutrient salvage pathway in pancreatic ductal adenocarcinoma exists.
Mon Apr 01 00:00:00 EDT 2019
Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity.
International journal of oncology
Yoshida M,Taguchi A,Kawana K,Ogishima J,Adachi K,Kawata A,Nakamura H,Sato M,Fujimoto A,Inoue T,Tomio K,Mori M,Nagamatsu T,Arimoto T,Koga K,Hiraike OW,Oda K,Kiyono T,Osuga Y,Fujii T
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Thymic exosomes promote the final maturation of thymocytes.
Scientific reports
Lundberg V,Berglund M,Skogberg G,Lindgren S,Lundqvist C,Gudmundsdottir J,Thörn K,Telemo E,Ekwall O
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Tue Nov 08 00:00:00 EST 2016
Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma.
Journal for immunotherapy of cancer
Patel MA,Kim JE,Theodros D,Tam A,Velarde E,Kochel CM,Francica B,Nirschl TR,Ghasemzadeh A,Mathios D,Harris-Bookman S,Jackson CC,Jackson C,Ye X,Tran PT,Tyler B,Coric V,Selby M,Brem H,Drake CG,Pardoll DM,Lim M
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Wed May 18 00:00:00 EDT 2016
Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Nature communications
Chen Q,Xu L,Liang C,Wang C,Peng R,Liu Z
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Fri Oct 21 00:00:00 EDT 2016
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive.
PLoS pathogens
Sanin DE,Prendergast CT,Bourke CD,Mountford AP
14-4771 was used in Flow cytometry/Cell sorting to investigate the role of skin CD4+ T cells in immune regulation after repeated pathogen exposure.
Fri May 01 00:00:00 EDT 2015
Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas.
Oncoimmunology
Ahn B,Kohanbash G,Ohkuri T,Kosaka A,Chen X,Ikeura M,Wang TC,Okada H
14-4771 was used in Flow cytometry/Cell sorting to investigate the role of HDC in the glioma microenvironment via maturation of myeloid cells and resulting activation of CD8(+) T cells.
Sun Nov 01 00:00:00 EDT 2015
STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment.
Cancer immunology research
Ohkuri T,Ghosh A,Kosaka A,Zhu J,Ikeura M,David M,Watkins SC,Sarkar SN,Okada H
14-4771 was used in Flow cytometry/Cell sorting to display a potential use of STING agonists for the development of effective immunotherapy.
Mon Dec 01 00:00:00 EST 2014
IL4 limits the efficacy of tumor-targeted antibody therapy in a murine model.
Cancer immunology research
Surana R,Wang S,Xu W,Jablonski SA,Weiner LM
14-4771 was used in Flow cytometry/Cell sorting to demonstrate that IL4 neutralisation enhances the efficacy of trastuzumab by influencing the phenotype of myeloid cells within the tumour microenvironment.
Sat Nov 01 00:00:00 EDT 2014
Combination of an agonistic anti-CD40 monoclonal antibody and the COX-2 inhibitor celecoxib induces anti-glioma effects by promotion of type-1 immunity in myeloid cells and T-cells.
Cancer immunology, immunotherapy : CII
Kosaka A,Ohkuri T,Okada H
14-4771 was used in Flow cytometry/Cell sorting to evaluate the therapeutic effects and underlying mechanisms of a combination regimen with an agonist CD40 mAb and the COX-2 inhibitor celecoxib.
Fri Aug 01 00:00:00 EDT 2014
Foxp3 expression in macrophages associated with RENCA tumors in mice.
PloS one
Devaud C,Yong CS,John LB,Westwood JA,Duong CP,House CM,Denoyer D,Li J,Darcy PK,Kershaw MH
14-4771 was used in Western Blotting to study how tumour-associated macrophages could express Foxp3.
Mon Nov 16 00:00:00 EST 2015
Foxp3 expression in macrophages associated with RENCA tumors in mice.
PloS one
Devaud C,Yong CS,John LB,Westwood JA,Duong CP,House CM,Denoyer D,Li J,Darcy PK,Kershaw MH
14-4771 was used in Western Blotting to study how tumour-associated macrophages could express Foxp3.
Mon Nov 16 00:00:00 EST 2015
Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1.
PloS one
Maneva-Radicheva L,Amatya C,Parker C,Ellefson J,Radichev I,Raghavan A,Charles ML,Williams MS,Robbins MS,Savinov AY
14-4771 was used in Immunofluorescence to reveal that the protein, DM199, may benefit type 1 diabetics by attenuating autoimmunity and improving beta cell health.
Wed Jun 10 00:00:00 EDT 2015
R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Kim MS,Kim TS
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Wed May 01 00:00:00 EDT 2013
Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle.
Molecular medicine (Cambridge, Mass.)
Eghtesad S,Jhunjhunwala S,Little SR,Clemens PR
14-4771 was used in Immunohistochemistry to assess the effects of rapamycin on the pathology of mdx mouse, a model for Duchenne muscular dystrophy.
Sun Mar 25 00:00:00 EDT 2012
Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle.
Molecular medicine (Cambridge, Mass.)
Eghtesad S,Jhunjhunwala S,Little SR,Clemens PR
14-4771 was used in Immunohistochemistry to assess the effects of rapamycin on the pathology of mdx mouse, a model for Duchenne muscular dystrophy.
Sun Mar 25 00:00:00 EDT 2012
Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection.
Journal of immunology (Baltimore, Md. : 1950)
McCarl CA,Khalil S,Ma J,Oh-hora M,Yamashita M,Roether J,Kawasaki T,Jairaman A,Sasaki Y,Prakriya M,Feske S
14-4771 was used in Flow cytometry/Cell sorting to reaffirm the critical role of ORAI1 for T cell function, and provide important insights into the in vivo functions of CRAC channels for T cell-mediated immunity.
Mon Nov 15 00:00:00 EST 2010
Effects of irradiating adult mdx mice before full-length dystrophin cDNA transfer on host anti-dystrophin immunity.
Gene therapy
Eghtesad S,Zheng H,Nakai H,Epperly MW,Clemens PR
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Immunohistochemistry
Wed Sep 01 00:00:00 EDT 2010
Effects of irradiating adult mdx mice before full-length dystrophin cDNA transfer on host anti-dystrophin immunity.
Gene therapy
Eghtesad S,Zheng H,Nakai H,Epperly MW,Clemens PR
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Immunohistochemistry
Wed Sep 01 00:00:00 EDT 2010
Enhanced selection of FoxP3+ T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Verhagen J,Gabrysová L,Minaee S,Sabatos CA,Anderson G,Sharpe AH,Wraith DC
14-4771 was used in Immunofluorescence to show that cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) is not required for the peripheral function of FoxP3(+) Treg cells.
Tue Mar 03 00:00:00 EST 2009
The initial phase of an immune response functions to activate regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
O'Gorman WE,Dooms H,Thorne SH,Kuswanto WF,Simonds EF,Krutzik PO,Nolan GP,Abbas AK
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2009
The initial phase of an immune response functions to activate regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
O'Gorman WE,Dooms H,Thorne SH,Kuswanto WF,Simonds EF,Krutzik PO,Nolan GP,Abbas AK
Published figure using FOXP3 monoclonal antibody (Product # 14-4771-80) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2009
GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo.
Journal of immunology (Baltimore, Md. : 1950)
van Olffen RW,Koning N,van Gisbergen KP,Wensveen FM,Hoek RM,Boon L,Hamann J,van Lier RA,Nolte MA
14-4771 was used in Flow cytometry/Cell sorting to study the role of glucocorticoid-induced TNF receptor family-related protein on activated and regulatory T cells.
Mon Jun 15 00:00:00 EDT 2009
Foxp3 processing by proprotein convertases and control of regulatory T cell function.
The Journal of biological chemistry
de Zoeten EF,Lee I,Wang L,Chen C,Ge G,Wells AD,Hancock WW,Ozkaynak E
14-4771 was used in Western Blotting to investigate Foxp3 processing in Tregs.
Fri Feb 27 00:00:00 EST 2009