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Invitrogen
FPGT Polyclonal Antibody
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FPGT Antibody (PA5-119127) in IHC (P)
Immunohistochemistry (Paraffin) analysis of FPGT in mouse kidney tissue using FPGT Polyclonal Antibody (Product # PA5-119127) (20 µg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Rabbit IgG polyclonal secondary antibody (2 µg/mL). DAB staining.
产品信息
PA5-119127
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein Fucose-1-Phosphate Guanylyltransferase. The antigen corresponds to amino acid range 314-513 of the target protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fucose-1-phosphate guanyltransferase; Fucose-1-phosphate guanylyltransferase; GDP-beta-L-fucose pyrophosphorylase; GDP-L-fucose diphosphorylase; GDP-L-fucose pyrophosphorylase
基因别名: 1700016E03Rik; FPGT; GFPP
UniProt ID: (Human) O14772, (Mouse) G5E8F4
Entrez Gene ID: (Human) 8790, (Mouse) 75540
