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Invitrogen
FPR2 Polyclonal Antibody
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FPR2 Antibody (PA5-33538) in IHC (P)
Immunohistochemical analysis of formalin-fixed paraffin-embedded human colon, uc, neutrophils in crypt abscess using a FPR2/FPRL1 polyclonal antibody (Product # PA5-33538) at a 8 ug/ml dilution. Heat-induced antigen retrieval was performed prior to staining.
产品信息
PA5-33538
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from C-terminus of human FPR2 / FPRL1.
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Chimpanzee, Monkey (94%) Orangutan, Marmoset (88%) Rabbit (81%).
靶标信息
Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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