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Invitrogen
FRAT1 Polyclonal Antibody
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FRAT1 Antibody (PA5-102990) in IHC (P)
Immunohistochemistry analysis of FRAT1 in human gastric cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with FRAT1 polyclonal antibody (Product # PA5-102990) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-102990
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FRAT1(Accession Q92837), corresponding to amino acid residues I213-S263.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total FRAT1.
靶标信息
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FRAT-1; Frequently rearranged in advanced T-cell lymphomas 1; Proto-oncogene FRAT1
基因别名: FRAT1
UniProt ID: (Human) Q92837
Entrez Gene ID: (Human) 10023
