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Invitrogen
FREM2 Polyclonal Antibody
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产品信息
PA5-55986
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TFDGVREMRE AFTVHLKPDE NMIAEMQLTK AIVYIEEMSS MADVTFPSVP QIVSLLMYDD TSKAKESAEP MSGYPVICIT ACNPKYSDYD KTGSICASEN INDTLTRYRW LISAPAGPDG VTSPMR
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 84%.
靶标信息
FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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