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Invitrogen
FRY Polyclonal Antibody
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产品信息
PA5-59655
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EDVLFGFTNF LLREVNDMHH TLLDSSLKLL LQLLTQWKLV IQTQGKVYEQ ANKIRNSELI ANGSSHRIQS ERGPHCSVLH AVE
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 87%.
靶标信息
The FRY gene encodes a protein known as furry homolog (FRY), a gene that is highly conserved across species and plays vital roles in cell division and differentiation. FRY is involved in the regulation of mitotic spindle orientation and cellular polarity, crucial for proper cell division and tissue organization. It is found within various tissues and has implications in neurodevelopment and cancer biology, where it influences cell structural properties and signaling pathways. Alterations in FRY expression or mutations can disrupt normal cell function, leading to aberrant cellular morphogenesis and developmental defects. In cancer studies, FRY is associated with tumor suppression, where loss of function contributes to uncontrolled cell proliferation. This gene interacts with other cellular components, such as the cytoskeleton and signaling proteins, orchestrating complex cellular processes essential for maintaining homeostasis and development.
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生物信息学
蛋白别名: furry homolog; Protein furry homolog; WUGSC:H_2G3A.1
基因别名: 13CDNA73; 214K23.2; bA207N4.2; bA37E23.1; C13orf14; CG003; FRY
UniProt ID: (Human) Q5TBA9
Entrez Gene ID: (Human) 10129
