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Invitrogen
FXN Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-69764
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide corresponding to a region of rat FXN
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 92%
靶标信息
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名: RGD1565754
Entrez Gene ID: (Rat) 499335
oxidative phosphorylation
heme biosynthetic process
cellular iron ion homeostasis
mitochondrion organization
adult walking behavior
aerobic respiration
embryo development ending in birth or egg hatching
response to iron ion
negative regulation of lipid storage
iron-sulfur cluster assembly
protein autoprocessing
proprioception
cellular cation homeostasis
positive regulation of mitochondrial membrane permeability
negative regulation of multicellular organism growth
cellular response to glucose starvation
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
[2Fe-2S] cluster assembly
[4Fe-4S] cluster assembly
positive regulation of axon extension
negative regulation of organ growth
mitochondrial iron ion transport
positive regulation of lyase activity
regulation of cytosolic calcium ion concentration
protein maturation
cellular response to hydrogen peroxide
cellular response to hypoxia
response to cisplatin
negative regulation of release of cytochrome c from mitochondria
inorganic ion homeostasis
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