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Invitrogen
Fab Kappa Light Chain VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (ABS1176)
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产品信息
MA562798
产品规格
种属反应
Human
宿主/亚型
Alpaca
/ VHH
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ABS1176
抗原
Recombinant human Fab
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Metal-chelate chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The Fab kappa light chain is a component of immunoglobulins characterized by specific interactions with the heavy chain regions within antibodies. The kappa light chain's role in antibody structure involves binding to heavy chains in the CH1 domain necessary for proper antibody assembly and secretion influencing biophysical properties and stability. Rapid affinity purification methods use Protein L to effectively segregate kappa light chain subtypes ensuring specificity in antibody recovery and purification processes. This light chain domain plays a crucial role in determining structural features avidity and specificity crucial for therapeutic antibody efficacy. Emerging technologies like Pro-L affinity purification focus on light chain control and mispairing avoidance which is essential in developing multispecific antibodies for therapeutic applications. The kappa light chain's interactions within antibody assemblies underscore its significance in antibody design and therapeutic use.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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