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MA1-43007 detects Factor V in bovine samples.
MA1-43007 has successfully been used in RIA, WB, ELISA, IA applications.
MA1-43007 was derived from bovine factor Va heavy chain.
Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activated protein C cofactor; Coagulation factor V; coagulation factor V (proaccelerin, labile factor); Factor 5; Factor5
基因别名: F5
UniProt ID: (Bovine) Q28107
Entrez Gene ID: (Bovine) 280687
分子生物学功能: oxidoreductase