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Invitrogen
Factor VII Polyclonal Antibody
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产品信息
PA1-74111
产品规格
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Factor VII from human plasma.
偶联物
形式
Liquid
浓度
10 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA1-74111 detects Factor VII from human samples.
PA1-74111 has been successfully used in ELISA and immunoelectrophoresis applications.
The PA1-74111 immunogen is Factor VII from human plasma.
靶标信息
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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