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Invitrogen
Factor VIII Monoclonal Antibody (012)
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产品信息
MA1-27389
产品规格
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
012
抗原
Purified, native human Factor VIII A2 domain.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
MA1-27389 detects Factor VIII A2 domain from human samples.
MA1-27389 has been successfully used in Western blot procedures. This antibody binds both human factor VIII and human factor VIIIa in solid-phase ELISA. It binds human factor VIII A2 domain in immunoblotting techniques.
The MA1-27389 immunogen is purified, native human Factor VIII A2 domain.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
靶标信息
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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