Invitrogen

Factor X Monoclonal Antibody (9051)

产品信息

MA1-43036

应用

建议稀释比

已发表文章

免疫印迹 (WB)

5 µg/mL

酶联免疫吸附实验 (ELISA)

5-10 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Rat / IgG

分类

Monoclonal

类型

Antibody

克隆号

9051

抗原

Mouse Factor X.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

8.0 mg/mL

纯化类型

Ammonium sulfate precipitation, Ion-exchange chromatography

保存液

50% water with 50% glycerol

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2231369

产品详细信息

MA1-43036 detects Factor X in mouse samples.

MA1-43036 has successfully been used in Western blot and ELISA applications.

MA1-43036 was derived from mouse factor X.

靶标信息

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。