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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
酶联免疫吸附实验 (ELISA) |
1:250-1:2,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
10 |
抗原 |
Recombinant Human Coagulation Factor X/F10 Protein |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS |
内含物 |
no preservative |
保存条件 |
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
RRID |
AB_2786254 |
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human Coagulation Factor X/F10.
Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activated factor Xa heavy chain; Coagulation factor X; Factor X heavy chain; Factor X light chain; factor Xa; prothrombinase; Stuart factor; Stuart-Prower factor
基因别名: F10; FX; FXA
UniProt ID: (Human) P00742
Entrez Gene ID: (Human) 2159
分子生物学功能:
serine protease
