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Nordic
Fibrinogen Polyclonal Antibody
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产品信息
GAM-FBG-7S
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse fibrinogen
偶联物
形式
Lyophilized
浓度
10 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute the lyophilized antiserum by adding 1 mL sterile distilled water.
The antiSerum does not cross-react with any other component of Mouse plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiSerum has not been tested in detail.
靶标信息
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fibg; Fibrinogen alpha chain; Fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma-chain; fibrinogen, B beta polypeptide; fibrinogen, gamma polypeptide; gamma-fibrinogen; MGC119422; MGC119423; MGC119425
基因别名: 2510049G14Rik; 3010002H13Rik; AI256424; ENSMUSG00000059807; Fga; Fgb; Fgg; Fib
UniProt ID: (Mouse) E9PV24, (Mouse) Q8K0E8, (Mouse) Q8VCM7
Entrez Gene ID: (Mouse) 14161, (Mouse) 110135, (Mouse) 99571
immune system process
cell-matrix adhesion
signal transduction
blood coagulation
hemostasis
platelet activation
positive regulation of heterotypic cell-cell adhesion
induction of bacterial agglutination
cellular protein complex assembly
innate immune response
positive regulation of vasoconstriction
positive regulation of exocytosis
positive regulation of protein secretion
protein polymerization
response to calcium ion
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
positive regulation of peptide hormone secretion
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of endothelial cell apoptotic process
