应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
Assay-dependent | - |
酶联免疫吸附实验 (ELISA) |
Assay-dependent | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG2b |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
1F3 |
抗原 |
Fibrin degradation products. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
4.2 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS, pH 7.4 |
内含物 |
0.09% sodium azide |
保存条件 |
4° C, do not freeze |
RRID |
AB_558927 |
MA1-20038 detects fibrinogen in human samples.
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epididymis secretory sperm binding protein Li 78p; fibg; Fibrinogen alpha chain; Fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen, A alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; MGC119422; MGC119423; MGC119425; testicular tissue protein Li 70
基因别名: FGA; FGB; FGG; Fib2; HEL-S-78p; PRO2061
UniProt ID: (Human) P02671, (Human) P02675, (Human) P02679
Entrez Gene ID: (Human) 2243, (Human) 2244, (Human) 2266
分子生物学功能:
intercellular signal molecule