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Invitrogen
Filamin 2 Polyclonal Antibody
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产品信息
PA5-88919
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 2160-2340 of human FLNC (NP_0014493)
偶联物
形式
Liquid
浓度
1.01 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: IPGNWFQMVS AQERLTRTFT RSSHTYTRTE RTEISKTRGG ETKREVRVEE STQVGGDPFP AVFGDFLGRE RLGSFGSITR QQEGEASSQD MTAQVTSPSG KVEAAEIVEG EDSAYSVRFV PQEMGPHTVA VKYRGQHVPG SPFQFTVGPL GEGGAHKVRA GGTGLERGVA GVPAEFSIWT R; Positive Samples: A-549, LO2, NIH/3T3; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein, Z line, cytoskeleton, myofibril, sarcomere
靶标信息
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ABP-280-like protein; ABP-L; ABP-L, gamma filamin; actin binding protein 280; Actin-binding-like protein; Filamin C gamma; filamin C, gamma; Filamin-2; Filamin-C; FLJ10186; FLN-C; gamma filamin; Gamma-filamin
基因别名: ABP-280; ABP280A; ABPA; ABPL; FLN2; FLNC; MFM5; MPD4
UniProt ID: (Human) Q14315
Entrez Gene ID: (Human) 2318
