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Immunogen sequence: PDGTEAEADV IENEDGTYDI FYTAAKPGTY VIYVRFGGVD IPNSPFTVMA TDGEVTAVEE APVNACPPGF RPWVTEEAYV PVSDMNGLGF KPFDLVIPFA; Positive Samples: HeLa, NIH/3T3, A-431, Mouse liver, Mouse kidney, Mouse uterus, Rat lung; Cellular Location: Cytoplasm, Z line, cell cortex, cytoskeleton, myofibril, sarcomere
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ABP-278; ABP-280 homolog; ABP-280-like protein; actin binding protein 278; Actin-binding-like protein; Beta-filamin; Fh1; filamin B, beta; Filamin homolog 1; filamin, beta; Filamin-3; Filamin-B; FilaminB; FLN-B; Larsen syndrome 1 (autosomal dominant); Thyroid autoantigen; Truncated ABP; Truncated actin-binding protein
基因别名: ABP-278; ABP-280; AL024016; AOI; FH1; FLN-B; FLN1L; FLN3; FLNB; LRS1; SCT; TABP; TAP
UniProt ID: (Human) O75369, (Mouse) Q80X90
Entrez Gene ID: (Human) 2317, (Mouse) 286940, (Rat) 306204