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Invitrogen
Flubendiamide Recombinant Mouse Monoclonal Antibody (6B1)
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Flubendiamide Antibody (MA566493) in SDS-PAGE
SDS-PAGE characterization of Flubendiamide under reducing conditions. Lane M: Protein marker (kDa); Lane FBD: Purified Flubendiamide Recombinant Monoclonal (Product # MA566493). Flubendiamide showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-525.
产品信息
MA566493
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6B1
抗原
Conjugate of FBD hapten and KLH.
偶联物
形式
Liquid
浓度
1.9 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Flubendiamide is the first commercial phthalic acid diamide insecticide, developed by Kabuskiki Kaisha, targeting the insect ryanodine receptor (RyR) with high specificity and mammalian safety. It acts as a conformation-sensitive activator of RyR, disrupting calcium ion regulation in insects, leading to muscle paralysis and death. Flubendiamide is extensively used in pest management due to its excellent insecticidal properties and has been pivotal in controlling various crop pests globally. However, resistance development in pests like the cotton bollworm Helicoverpa armigera poses challenges to its efficacy. Additionally, studies have shown that flubendiamide can provoke oxidative stress and inflammation in human cells, indicating potential health hazards. Its structure includes a phthalic acid diamide core, which is crucial for its function and interaction with RyR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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