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Invitrogen
Fludioxonil Recombinant Mouse Monoclonal Antibody (2E12)
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Fludioxonil Antibody (MA566492) in SDS-PAGE
SDS-PAGE characterization of Fludioxonil under reducing conditions. Lane M: Protein marker (kDa); Lane FDX: Purified Fludioxonil Recombinant Monoclonal (Product # MA566492). Fludioxonil showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-592.
产品信息
MA566492
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2E12
抗原
Conjugate of FDX hapten and KLH.
偶联物
形式
Liquid
浓度
7.5 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Fludioxonil is a phenylpyrrole fungicide extensively utilized in agriculture to control fungal diseases in crops. It functions by disrupting the osmotic regulation in fungal cells, leading to cell death. Fludioxonil targets the histidine kinase in the fungal two-component signal transduction system, which is crucial for the fungus's ability to adapt to environmental changes. The chemical structure of fludioxonil includes a pyrrole ring, which is responsible for its fungicidal activity. Despite its effectiveness in agriculture, fludioxonil poses potential risks to aquatic ecosystems and human health, as it can induce oxidative stress and cytoskeleton disruption, particularly affecting neural and cardiac cells. Studies have shown that fludioxonil can lead to mitochondrial dysfunction and apoptosis, highlighting the importance of evaluating its environmental and health impacts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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