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Invitrogen
Folic acid Recombinant Mouse Monoclonal Antibody (2B7)
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Folic acid Antibody (MA566482) in SDS-PAGE
SDS-PAGE characterization of Folic acid under reducing conditions. Lane M: Protein marker (kDa); Lane FAS: Purified Folic acid Recombinant Monoclonal (Product # MA566482). Folic acid showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-265.
产品信息
MA566482
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2B7
抗原
Conjugate of FAS hapten and KLH.
偶联物
形式
Liquid
浓度
5.3 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Folic acid, a B-vitamin essential for numerous biochemical processes, plays a key role in DNA synthesis and repair, as well as methylation, which is crucial for genome regulation and normal mammalian development. It functions primarily as a methyl-group donor and is involved in critical biological processes such as cell division and gene expression regulation. This vitamin is integral to folate metabolism, which has significant implications for DNA methylation and thereby impacts epigenetic modifications. Variations in dietary intake and functional polymorphisms in the genes encoding folate metabolism enzymes can influence its efficacy, making it a potential factor in cancer susceptibility and other diseases. Folic acid deficiency is common and can arise from poor diet, malabsorption, alcohol use, obesity, and kidney failure. Due to its protective effects against neural tube defects and ischemic events, folic acid fortification in foods has been adopted in many countries. The molecular interaction of folic acid with DNA and RNA occurs at different sites, highlighting its multifaceted role in cellular processes. Overall, folic acid's impact on DNA methylation underscores its importance in health and disease prevention.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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