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Clone 33B12 and 117C9 detect overlapping epitopes on the Forssman glycolipid hapten (GalNA1- c3aG alNAcD1 -3GalaI-4GalB1-4GlcBl-lCer). Clone 33B12 reacts with the terminal sugar sequence GalNAcd-3GalNAc and is specific for Forssman antigen.
The antibody may be stored at 4°C. For prolonged storage prepare appropriate aliquots and store at or below -20°C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.
Has lost the ability to synthesize Forssman glycolipid antigen (FORS1/FG. Might have acquired an alternative function in glycosphingolipid metabolism, but it remains to be established. It appears to have drifted more slowly than confirmed pseudogenes in the glycosyltransferase 6 family, suggesting that it has remained under evolutionary pressure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Forssman glycolipid synthase; forssman glycolipid synthetase; Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
基因别名: Fgs; Fs; Gbgt1
UniProt ID: (Mouse) Q8VI38
Entrez Gene ID: (Mouse) 227671