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Abnova
G0S2 Polyclonal Antibody, MaxPab™
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G0S2 Antibody (H00050486-B01P) in WB
Western Blot analysis of G0S2 expression in transfected 293T cell line (H00050486-T01) by G0S2 MaxPab polyclonal antibody.
Lane 1: G0S2 transfected lysate(11.44 KDa).
Lane 2: Non-transfected lysate.
Lane 1: G0S2 transfected lysate(11.44 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00050486-B01P
产品规格
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
G0S2 (AAH09694, 1 a.a. approximately 103 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: METVQELIPL AKEMMAQKRK GKMVKLYVLG SVLALFGVVL GLMETVCSPF TAARRLRDQE AAVAELQAAL ERQALQKQAL QEKGKQQDTV LGGRALSNRQ HAS
靶标信息
The G(0)-G(1) switch gene 2 (G0S2) codes for a mitochondrial protein that is important in apoptosis, lipolysis, and triacylglycerol hydrolysis. In adipocytes, G0S2 binds to adipose triglyceride lipase and decreases the breakdown of lipid droplets. In Crohn's colitis, the presence of G0S2 is increased in correlation to the amount of non-converted lipid in waste. In squamous lung cancer, mutations in the G0S2 gene are common. In breast cancer, epigenetic silencing of G0S2 occurs, and normal apoptotic regulation of aberrant cells is negatively impacted. However, when G0S2 is not epigenetically modified, it is the best mediator of the Bcl-2/Bax heterodimer, resulting in apoptosis of cancerous cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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