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Antibodies Inc
GABA-A-R-Gamma2L Monoclonal Antibody (N452/69)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
75-442
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
N452/69
抗原
Fusion protein amino acids 360-445 (cytoplasmic C-terminus) of human GABA-A-R-Gamma2L (accession number P18507-2) produced recombinantly in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
GABA-A-R-Gamma2L refers to the long splice variant of the gamma2 subunit of the GABA-A receptor, which is a major inhibitory neurotransmitter receptor in the central nervous system. The gamma2 subunit is critical for the receptor's proper assembly, trafficking, and synaptic localization, and it influences the receptor's pharmacological properties, including its sensitivity to benzodiazepines. Mutations or alterations in the gamma2 subunit, including the gamma2L variant, can affect inhibitory neurotransmission and are associated with neurological disorders such as epilepsy and anxiety.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GABA(A) receptor subunit gamma-2; GABAAR subunit gamma-2; gamma-aminobutyric acid A receptor, gamma 2; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2; gamma-aminobutyric acid A receptor, gamma 2; Gamma-aminobutyric acid receptor subunit gamma-2
基因别名: GABAA-R; Gabrg-2; GABRG2; gamma2
UniProt ID: (Mouse) P22723, (Rat) P18508
Entrez Gene ID: (Mouse) 14406, (Rat) 29709
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
