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Invitrogen
GABRG1 Polyclonal Antibody
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产品信息
PA5-89695
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
形式
Liquid
浓度
0.88 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: HSCPLEFSSY GYPKNEIEYK WKKPSVEVAD PKYWRLYQFA FVGLRNSTEI THTISGDYVI M; Positive Samples: U-87MG, Mouse brain; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
靶标信息
Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. Gabrg1 is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. Structurally, Gabrg1 are pentameric proteins, consisting of five subunits belonging to different families. Diseases associated with GABRG1 include Alcohol Dependence.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GABA(A) receptor subunit gamma-1; GABA(A) receptor, gamma; GABAAR gamma1; GABAAR subunit gamma-1; Gabeg1; gamma-1 polypeptide; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 1; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 1; gamma-aminobutyric acid A receptor, gamma 1; Gamma-aminobutyric acid receptor subunit gamma-1
基因别名: GabaA; GabaA/BZ; GABRG1
UniProt ID: (Human) Q8N1C3, (Rat) P23574, (Mouse) Q9R0Y8
Entrez Gene ID: (Human) 2565, (Rat) 140674, (Mouse) 14405
