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Peptide Sequence: MSWRGRSTYY WPRPRRYVQP PEMIGPMRPE QFSDEVEPAT PEEGEPATQR QDPAAAQEGE DEGASAGQGP KPEADSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE EMRSHYVAQT GILWLLMNNC FLNLSPRKP
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The GAGE1 cDNA contains a 143-bp insertion, located in the coding sequence near the termination codon, that is absent from the other cDNAs. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. An alternatively spliced transcript variant has been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Antigen MZ2-F; Cancer/testis antigen 4.1; cancer/testis antigen family 4, member 1; CT4.1; G antigen 1; GAGE-1; MZ2-F antigen
基因别名: CT4.1; GAGE-1; GAGE1
UniProt ID: (Human) P0DTW1
Entrez Gene ID: (Human) 2543