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产品信息
OSG00024G-500UG
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from the n-terminal region of human Axonal membrane protein GAP-43 (Neuromodulin, growth-associated protein 43) conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
纯化类型
Ammonium sulfate precipitation
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat, mouse, zebra fish and chicken.
Specificity of this antibody: GAP-43.
靶标信息
GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; growth accentuating protein 43; Growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1
基因别名: B-50; Basp2; GAP-43; GAP43; PP46
UniProt ID: (Human) P17677, (Rat) P07936, (Mouse) P06837
Entrez Gene ID: (Human) 2596, (Rat) 29423, (Mouse) 14432
nervous system development
axon guidance
glial cell differentiation
axon choice point recognition
regulation of growth
tissue regeneration
cell fate commitment
regulation of filopodium assembly
axon development
multicellular organism development
cell differentiation
protein kinase C-activating G-protein coupled receptor signaling pathway
response to wounding
