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Proteintech
GCNF Polyclonal Antibody
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产品信息
12712-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GCNF Fusion Protein Ag3395 (1-350 aa encoded by BC030600)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody specifically reacts with the 55 kDa NR6A1 protein.
Immunogen sequence: MERDEPPPS GGGGGGGSAG FLEPPAALPP PPRNGFCQDE LAELDPGTND RAEQRTCLIC GDRATGLHYG IISCEGCKGF FKRSICNKRV YRCSRDKNCV MSRKQRNRCQ YCRLLKCLQM GMNRKAIRED GMPGGRNKSI GPVQISEEEI ERIMSGQEFE EEANHWSNHG DSDHSSPGNR ASESNQPSPG STLSSRSVEL NGFMAFREQY MGMSVPPHYQ YIPHLFSYSG HSPLLPQQAR SLDPQSYSLI HQLLSAEDLE PLGTPMLIED GYAVTQAELF ALLCRLADEL LFRQIAWIKK LPFFCELSIK DYTCLLSSTW QELILLSSLT VYSKQIFGEL ADVTAKYSPS D (1-350 aa encoded by BC030600)
靶标信息
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GCNF; Germ cell nuclear factor; germ cell nuclear factor variant 1; h hRTR; mGCNF; Nuclear receptor subfamily 6 group A member 1; nuclear receptor subfamily 6, group A, member 1; retinoic acid receptor-related testis-associated receptor; Retinoid receptor-related testis-specific receptor; RTR
基因别名: 1700113M01Rik; CT150; GCNF; GCNF1; hGCNF; hRTR; NCNF; NR61; NR6A1; RTR
UniProt ID: (Human) Q8NHQ0, (Mouse) Q64249
Entrez Gene ID: (Human) 2649, (Rat) 362125, (Mouse) 14536
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
zinc ion binding
protein homodimerization activity
sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
metal ion binding
negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
gamete generation
spermatogenesis
cell proliferation
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
steroid hormone mediated signaling pathway
multicellular organism development
cell differentiation
