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Invitrogen
GCNT1 Polyclonal Antibody
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GCNT1 Antibody (PA5-109759) in WB
Western blot analysis of GCNT1 in extracts of various cell lines. Samples were incubated with GCNT1 Polyclonal antibody (Product # PA5-109759) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-109759
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GCNT1 (NP_001091103.1).
偶联物
形式
Liquid
浓度
1.94 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FVSVRHLELA GENPSSDINC TKVLQGDVNE IQKVKLEILT VKFKKRPRWT PDDYINMTSD CSSFIKRRKY IVEPLSKEEA EFPIAYSIVV HHKIEMLDRL LRAIYMPQNF YCIHVDTKSE DSYLAAVMGI ASCFSNVFVA SRLESVVYAS WSRVQADLNC MKDLYAMSAN WKYLINLCGM DFPIKTNLEI VRKLKLLMGE NNLETERMPS HKEERWKKRY EVVNGKLTNT GTVKMLPPLE TPLFSGSAYF VVSREYVGYV L
靶标信息
Glycosylation is one of the most universal but at the same time complex protein modifications. Modification with sugar moeties can be both co- translational and post- translational, occurring in the endoplasmatic reticulum and golgi. Three different forms of glycosylation can be distinguished: N-linked oligosaccharides, O-linked oligosaccharides and glycosyl- phosphatidylinositol (GPI-) anchors. Glycosylation results in thousands of distinct, bioactive glycoproteins resident throughout the cell that strongly determine protein-protein, carbohydrate-protein, membrane, and adhesion properties. Diseases associated with glycosylation defects include Congenital disorders of glycosylation, (CDG), also known as carbohydrate deficient glycoprotein syndromes, and diseases associated with advanced aging.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; beta-1,6-N-acetylglucosaminyltransferase; C2GlcNAcT; C2GNT; C2GnT-L; Core 2 beta-1,6-N-acetylglucosaminyltransferase; core 2 beta-1,6-N-acetylglucosaminyltransferase I; core 2 beta1,6 N-acetylglucosaminyltransferase-I; core 2 branching enzyme; core 2 GnT; Core 2-branching enzyme; Core2-GlcNAc-transferase; glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase); Leukocyte type core 2 beta-1,6-N-acetylglucosaminyltransferase
基因别名: C2GNT; C2GNT-L; C2GNT1; G6NT; GCNT1; NACGT2; NAGCT2
UniProt ID: (Human) Q02742
Entrez Gene ID: (Human) 2650
