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Antibody detects endogenous levels of total GDF1.
Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Embryonic growth/differentiation factor 1; GDF-1
基因别名: AI385651; DORV; DTGA3; Gdf-1; GDF1; RAI
UniProt ID: (Human) P27539, (Mouse) P20863
Entrez Gene ID: (Human) 2657, (Mouse) 14559, (Rat) 306351