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Invitrogen
GDNF Polyclonal Antibody
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GDNF Antibody (PA5-77537) in ICC/IF
Immunocytochemistry analysis of GDNF in paraffin-embedded rat C6 glioma cells. A) Samples were probed with GDNF polyclonal antibody (Product # PA5-77537) using a dilution of 1:200, and incubated with goat-anti-rabbit-AlexaFluor-555 and Hoechst. B) Live cell image.
产品信息
PA5-77537
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)DDNLVYHILRKHSAKR, corresponding to amino acid residues 192-207 of human GDNF (precursor)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
靶标信息
GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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