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Immunogen sequence: HSKHCLSVET EADSGQAGPY ENWMLEPALA TGEELPELTL LTTLLEGPGD KTQPPEEETL SQAPESEEEQ KKKALERSMY V
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.
The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange. The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Guanine nucleotide exchange factor GEFT; p63RhoGEF; RAC/CDC42 exchange factor; Rac/Cdc42/Rho exchange factor GEFT; Rho guanine nucleotide exchange factor (GEF) 25; Rho guanine nucleotide exchange factor 25; RhoA/RAC/CDC42 exchange factor; RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT
基因别名: ARHGEF25; GEFT; p63RhoGEF
UniProt ID: (Human) Q86VW2
Entrez Gene ID: (Human) 115557
分子生物学功能: guanyl-nucleotide exchange factor