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Invitrogen
GFAP Polyclonal Antibody
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产品信息
PA1-18031
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GFAP isolated from bovine spinal cord.
偶联物
形式
Liquid
保存条件
4°C
产品详细信息
PA1-18031 detects Glial Fibrillary Acid Protein from human, mouse and avian samples.
PA1-18031 is predicted to detect Gial Fibriallary Acid Protein from Cat, Guinea Pig, Hamster, Human, Kangaroo, Monkey, Rabbit, Sheep.
PA1-18031 has been successfully used in immunohistochemistry applications.
The PA1-18031 immunogen is GFAP isolated from bovine spinal cord.
靶标信息
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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