Invitrogen

GFM2 Polyclonal Antibody

产品信息

PA5-50026

应用	建议稀释比	已发表文章
免疫印迹 (WB)	1:500-1:3,000	-
免疫细胞化学 (ICC/IF)	1:100-1:500	-

产品规格
种属反应	Human, Mouse
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	Synthesized peptide derived from internal of human GFM2. 查看免疫原
偶联物	Unconjugated
形式	Liquid
浓度	1 mg/mL
纯化类型	Antigen affinity chromatography
保存液	PBS, pH 7.4, with 50% glycerol
内含物	0.02% sodium azide
保存条件	-20°C
RRID	AB_2635479

产品详细信息

The antibody detects endogenous levels of total GFM2 protein.

靶标信息

GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: EF-G2mt; Elongation factor G 2, mitochondrial; Elongation factor G2; G elongation factor; G elongation factor, mitochondrial 2; GFM2; hEFG2; mEF-G 2; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; Ribosome-releasing factor 2, mitochondrial; RRF2mt

基因别名: 6530419G12Rik; A930009M04Rik; EF-G2mt; EFG2; GFM2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF2; RRF2mt

UniProt ID: (Human) Q969S9, (Mouse) Q8R2Q4

Entrez Gene ID: (Human) 84340, (Mouse) 320806

分子生物学功能: translation elongation factor