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Invitrogen
GFRAL Polyclonal Antibody
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产品信息
PA5-61491
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human GFRAL
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: KWNLTTRSHH GFKGMWSCLE VAEACVGDVV CNAQLASYLK ACSANGNPCD LKQCQAAIRF FYQNIPFNIA QMLAFCDCAQ SDI
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 81%.
靶标信息
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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