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Proteintech
GGH Polyclonal Antibody
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产品信息
13264-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GGH Fusion Protein Ag3939 (23-318 aa encoded by BC025025)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LSRPHGDTA KKPIIGILMQ KCRNKVMKNY GRYYIAASYV KYLESAGARV VPVRLDLTEK DYEILFKSIN GILFPGGSVD LRRSDYAKVA KIFYNLSIQS FDDGDYFPVW GTCLGFEELS LLISGECLLT ATDTVDVAMP LNFTGGQLHS RMFQNFPTEL LLSLAVEPLT ANFHKWSLSV KNFTMNEKLK KFFNVLTTNT DGKIEFISTM EGYKYPVYGV QWHPEKAPYE WKNLDGISHA PNAVKTAFYL AEFFVNEARK NNHHFKSESE EEKALIYQFS PIYTGNISSF QQCYIFD (23-318 aa encoded by BC025025)
靶标信息
Gamma-Glutamyl hydrolase (GGH) is a homodimeric protein that catalyzes the cleavage of the gamma-glutamyl chain of folylpoly-gamma-glutamyl substrates and is a central enzyme in folyl and antifolyl poly-gamma-glutamate metabolism. The activities of the baculovirus-expressed enzyme and the enzyme from HL-60 cells were similar on methotrexate polyglutamates. GGH is expressed in a variety of human tumors and correlates with poor prognosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Conjugase; FGPH; Folylpolyglutamate hydrolase; Gamma-Glu-X carboxypeptidase; Gamma-glutamyl hydrolase; gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase); GH
基因别名: gamma-GH; GGH; GH
UniProt ID: (Human) Q92820, (Mouse) Q9Z0L8, (Rat) Q62867
Entrez Gene ID: (Human) 8836, (Mouse) 14590, (Rat) 25455
