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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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Recommended positive controls: HePG2.
Predicted reactivity: Mouse (91%), Rat (84%), Xenopus laevis (86%), Chicken (85%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Glycine cleavage system P protein; glycine cleavage system protein P; Glycine decarboxylase; glycine decarboxylase P-protein; glycine decarboxylase, glycine cleavage system protein P); Glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); Glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; RP11-472F14.1
基因别名: D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; HYGN1
UniProt ID: (Human) P23378, (Mouse) Q91W43
Entrez Gene ID: (Human) 2731, (Mouse) 104174, (Rat) 309312
分子生物学功能: dehydrogenase