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Immunogen sequence: ANILPDIENE DFIKDCVRIH NKFRSEVKPT ASDMLYMTWD PALAQIAKAW ASNCQFSHNT RLKPPHKLHP NFTSLGENIW TGSVPIFSVS SAITNWYDEI QDYDFKTRIC KKVCGHYTQ; Positive Samples: Rat lung; Cellular Location: Membrane, Single-pass membrane protein
The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer. The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.