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Immunogen sequence: ANILPDIENE DFIKDCVRIH NKFRSEVKPT ASDMLYMTWD PALAQIAKAW ASNCQFSHNT RLKPPHKLHP NFTSLGENIW TGSVPIFSVS SAITNWYDEI QDYDFKTRIC KKVCGHYTQ; Positive Samples: Rat lung; Cellular Location: Membrane, Single-pass membrane protein
The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer. The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GLI pathogenesis-related 1 (glioma); glioma pathogenesis-related protein 1
Entrez Gene ID: (Rat) 299783