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Product Details
PA5-56749
产品规格
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Recombinant protein corresponding to Human GLMN
Conjugate
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2642037
Product Specific Information
Immunogen sequence: LSAIGHPFPK MIFNHGRKKR TWNYLEFEEE ENKQLADSMA SLAYLVFVQG IHIDQLPMVL SPLYLLQFNM GHIEVFLQRT EESV
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 77%.
Target Information
This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: FAP; FK506-binding protein-associated protein; FKBP-associated protein; Glomulin
Gene Aliases: FAP; FAP48; FAP68; FKBPAP; GLML; GLMN; GVM; VMGLOM
UniProt ID: (Human) Q92990
Entrez Gene ID: (Human) 11146
Molecular Function:
ubiquitin-protein ligase
vasculogenesis
neural tube closure
negative regulation of protein ubiquitination
regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of gene expression, epigenetic
negative regulation of T cell proliferation
positive regulation of phosphorylation
muscle cell differentiation
positive regulation of interleukin-2 biosynthetic process
positive regulation of cytokine secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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